Dmitri holds Vanessa hostage at the citadel. He tells Vanessa that something life-changing now begins and that he plans to learn everything there is to learn about her blood. He also reveals Vanessa’s true identity — she is a Van Helsing.

Dr. Sholomenko approaches the chained Vanessa. Vanessa asks him to help her, but he refuses because he wants to experiment on her. Using her blood as a weapon, he is helping to create day-walkers. He whispers to be patient and wait for her chance. He then loosens the belt tying her hand and leaves.

Meanwhile, Mohamad reunites with Sheema. Vanessa tries to escape, but Dmitri and Rebecca stop her.

Mohamad and Sheema talk about how Sheema got her room and food. She says they both could stay at the citadel. Mohamad tells her he did everything to get her out. But Sheema does not want to get out. She likes it in the citadel. Mohamad tells her he is leaving.

Dr. Sholomenko informs Dmitri, Antonasia, and Rebecca that he is ready to proceed with the removal of Vanessa’s eggs. Dmitri gives him the go signal. Dmitri asks Rebecca for any news on the Resistance. Rebecca lies to him.

At the Resistance settlement, a rumor that Vanessa is in the citadel reaches Taka. He is going back to check it out. Flesh suggests that they should attack before the vampires do anything to her.

Dr. Sholomenko brings a bag of blood to Vanessa and tells her to feed on it. Dmitri tells Vanessa that her mother also wanted to kill him. She asks him what he knows about her mother. Dmitri does not answer. Instead, he orders her to feed. Dr. Sholomenko wants to find out what effect blood has on her powers.

Mohamad visits Vanessa. Vanessa expresses her disappointment with his betrayal, saying she trusted him with her life. Mohamad apologizes and explains he had to do it. But Vanessa refuses to accept his explanation. Mohamad breaks the news that Sheema likes working for the vampires, and she does to want to leave the citadel. Vanessa says she is sorry for him because he sold his soul for nothing and asks him to go. Mohamad hands her a small knife before he leaves. Vanessa then stabs herself in the heart.

Dmitri reveals that Vanessa’s people have consistently and relentlessly hunted vampires for centuries. He expresses his admiration and respect to her great great great grandfather, Abraham. He tells her that her mother was a real warrior until she had a child. That her mother hid Vanessa before she died.

Taka arrives at the citadel. Rebecca welcomes him. Taka informs her that the Resistance is going to tear the citadel down with her help. Rebecca wants Taka to attack the citadel the next day. She wants to take Vanessa from Dmitri, so she could use her. She offers Taka an island off-limits to any vampire in exchange for his help. They agree to get rid of Dmitri first.

Vanessa is starving in her cell. She decides to finally give in and drink the blood. The blood boosts her super powers.

Taka briefs his followers on the coordinated attack. He orders them to kill everyone at the citadel. Flesh steps in and asks if he intends to kill Vanessa, too. Taka answers in the affirmative. Flesh declares that he is going to the citadel to save her, not to kill her.

Mohamad packs Sheema’s things. Sheema gets mad at him and tries to convince him that the citadel is a safer place than anywhere else. Mohamad insists that they should go. Sheema tells him that the citadel is about to be attacked, and she will help stop them. But Mohamad does not budge. Sheema then knocks him off with a vase.

Vanessa fights Dmitri. Dmitri runs before she could pull his heart out. She then fights with Rebecca. The Resistance attacks the citadel. Rebecca gets the chance to run from Vanessa. Vanessa followed suit. Taka meets with the injured Dmitri. Taka reveals to him that Rebecca betrayed him. Dmitri laughs when he learns that Rebecca offered Taka the Fox Island, saying it does not exist. Before Taka kills him, he offers Taka a deal.

Vanessa follows Rebecca to a room. She finally sees her daughter Dylan. Now a vampire, and in the hands of Rebecca.

Back at the farm, Axel emerges as a vampire.

Julius holds Magdalene hostage for her failure to bring him the newborn. Magdalene tells him that the arrangement was broken by the woman he seeks. She offers to take Julius to Vanessa.

Vanessa, Susan, Mohamad, and Sam arrive at Susan’s family farm but no one is there. Susan discovers that her mother died before The Rising, but her father never told her about it. At the attic, they find a radio with a broken mic. Someone on the other side communicates to them and tells them that Denver is the place to go. The news gives them hope. While they discuss what to do next, a noise from outside interrupts them. Susan’s father, now-turned-vampire, feeds on their horse Strider. They tie Susan’s father in the barn and decides what to do with him. Susan shots her father in the head. Vanessa, Mohamad, and Sam look for Susan. Sam found her in the woods, comforts her, and kills her. He then cut her finger.

Elsewhere, the sun burns Dmitri’s hands. Rebecca promises him that they will walk in the sunshine together soon. Dmitri is getting tired of Rebecca’s promises. He pressures her to make her promises a reality. She reassures him she knows the way.

Mohamad searches for Susan inside the house. He checks on Sam’s backpack and finds his collection of fingers. Mohamad attempts to tell Vanessa. Sam admits to them that he killed Susan before could Mohamad reveal that he is the killer. Vanessa finds Susan’s body in the woods. She asks Sam why he has killed Susan. Sam confesses it is just the way he is since he was a boy. Vanessa and Mohamad take Sam to the woods. Sam tries to tell Vanessa Mohamad’s secret. Mohamad attacks him. Vanessa and Mohamad leave Sam to die in the woods.

Rebecca confides to Dmitri about the human’s plan to attack their fortress and use the sunlight as a weapon. She suggests they double their efforts to capture Vanessa. Dmitri disapproves of her ideas and tells her that a plan is already in motion.

In the woods, the mortally-injured Sam is bleeding. A feral closes in as he tries to crawl his way to safety. The feral catches up with Sam and bites him. Back at Susan’s farm, Vanessa and Mohamad bury Susan. They hear Sam’s scream from a distance. Vanessa decides to go to Denver and suggests they take their separate ways. Before Mohamad could finish telling her his plans, the deaf Sam screams that he can hear them. Vanessa and Mohamad run for their lives. Sam digs Susan’s grave and feeds on her.

Vanessa maps the blood on the floor and wraps John’s body with a white sheet. Axel and Flesh arrive to help her out. Vanessa feels guilty for killing John. She justifies her actions and says that what she did is necessary. Axel agrees with her. Axel and Flesh carry the body to the kitchen. Flesh thanks Axel for keeping them safe. Very foul smell exudes when Axel opens the freezer. Rotting dead bodies are inside. Vanessa goes to her room and comforts Susan.

Doc examines the dead bodies to find out what happened to them. She instructs Axel and Gorman to put the bodies in the quarantine zone. While Axel piles up the corpses, Vanessa thanks him for protecting her during the past three years. They also talk about Vanessa’s past that Axel read about on her files. Vanessa asks for her files, but Axel said he does not have it. Pissed, Vanessa then locks him in the quarantine zone. A feral appears and Axel shoots it before it runs away.

While on the woods, Mohamad meets a girl named Emma. She offers Mohamad food. Emma is not afraid of the vampires.

Back at The Farm, Susan and Axel hunt the feral in the quarantine zone. They find a bloody room, but they could not find the feral.

Rebecca arrives at the human settlement to deliver Quaid. Dr. Sholomenko tells everyone that Quaid is a traitor.

Doc discovers that The Farm is filled with radiation. She passes out before she could tell anyone. Meanwhile, the group is discussing what to do with the feral. Gorman decides that he will find it. Axel and the rest of the group found Doc lying on the floor. She tells them that the whole place is contaminated with radiation and that they have to get off the place or they all die soon. But, they cannot get out because the only way in and out of the bunker is blocked.

Taka questions Quaid. Sheema tells him that Quaid is a traitor. Quaid tries to talk her way out of it but Taka shoots her.

At The Farm, Doc confesses to Axel that on the day she was bitten, she was not trying to save Smitty from the vampires. Contrary to Axel’s belief, she was trying to shut the door on him. Axel comforts her.

Luckily for the group, Sam discovers a hidden way out of the bunker. But Gorman is missing, and Doc decides to look for him. Axel accompanies her. They go back to the quarantine zone. Axel goes in while Doc guards the door. Axel finds the feral lying lifeless on the floor. Meanwhile, Vanessa and the rest of the group successfully escape from the vampires outside The Farm. Gorman, now a vampire, then attacks Axel. Doc anxiously waits by the door. When she sees Axel fighting with Gorman, she panics. She shuts the door on Axel, as she did on Smitty, and runs out of the facility. She then tells everyone Axel is dead.

Vanessa finds her missing file at the truck and discovers something about her past. The group hears the bell ringing. They have nowhere else to go, so they decide to check it out.